Emeritus Professor Lynnette Robin Ferguson
D.Phil. (Oxon.), DSc., QSO, FNZIFST, FRSNZ
Lynnette Ferguson obtained her D.Phil.(Oxon) (the equivalent of a PhD) from Oxford University, working on the subject of DNA damage, DNA repair and mutagenesis in yeast. After her return to New Zealand, she began working as part of the Auckland Cancer Society Research Centre, using mutagenicity testing as a predictor of carcinogenesis, with particular focus on the New Zealand situation. In 2000, she took on a 50% role as Head of a new Discipline of Nutrition at the University of Auckland. In more recent years, she has considered the interplay between genes and diet in the development of chronic disease, with particular focus on Inflammatory Bowel Disease, a cancer-prone condition, and also in prostate cancer. As programme leader for the multidisciplinary-multiorganisation Nutrigenomics New Zealand, she worked with a range of others to bring nutrigenomics tools and potential to the New Zealand science scene. She has supervised more than 40 students to the successful completion of B.tech, MSc or PhD. Her laboratory regularly supervises 2-3 summer students each year. She is the author or co-author of more than 350 peer reviewed publications as chapters in books or articles in international journals. She serves on the Editorial Boards of several major journals.
Research | Current
Lynnette's current research considers the interplay between genes and diet in the development of chronic disease, with particular focus on Inflammatory Bowel Disease, a cancer-prone condition and also in both colorectal and prostate cancer. As programme leader for the multidisciplinary-multiorganisation Nutrigenomics New Zealand, she has worked with a range of others across The university of Auckland, Plant and Food Research and Agresearch Ltd, to bring nutrigenomics tools and potential to the New Zealand science scene. http://www.nutrigenomics.org.nz/ Research interests: Gene-diet interactions in the development of chronic disease, Inflammatory Bowel Diseases, Colorectal cancer, Prostate cancer
Teaching | Current
Offers projects for MEDSCI701 and 702, co-supervises MSc and PhD projects
Queens Service Order in Public Health
Fellow, New Zealand Institute of Food Science and Technology
Fellow, Royal Society of New Zealand
Selected publications and creative works (Research Outputs)
- Karunasinghe, W. P., Wang, A., Vaidyanathan, V., & Ferguson, L. (2018). Supplemented selenium for prostate health varies with genetic polymorphisms and dietary mineral interaction-- proof of concept!. Queenstown, New Zealand. 25 August - 26 August 2018. Related URL.
- Ferguson, L. R., Karunasinghe, N., & Vaidayanathan, V. (2018). Genomic Instability and Prostate Cancer Risk in New Zealand. Paper presented at 49th Annual Meeting of the Environmental-Mutagenesis-and-Genomics-Society (EMGS) - Maintaining Genomic Integrity in the Face of Environmental Insult, San Antonio, TX. 22 September - 26 September 2018. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS. (pp. 1).
- Peng, Y., Bishop, K. S., Ferguson, L. R., & Quek, S. Y. (2018). Screening of Cytotoxicity and Anti-Inflammatory Properties of Feijoa Extracts Using Genetically Modified Cell Models Targeting TLR2, TLR4 and NOD2 Pathways, and the Implication for Inflammatory Bowel Disease. Nutrients, 10 (9).10.3390/nu10091188
Other University of Auckland co-authors: Karen Bishop, Siew-Young Quek
- Momozawa, Y., Dmitrieva, J., Théâtre E, Deffontaine, V., Rahmouni, S., Charloteaux, B., ... Gori, A.-S. (2018). IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes. Nature communications, 9 (1)10.1038/s41467-018-04365-8
- Ordovas, J. M., Ferguson, L. R., Tai, E. S., & Mathers, J. C. (2018). Personalised nutrition and health. BMJ (Clinical research ed.), 36110.1136/bmj.k2173
- Vaidyanathan, V., Naidu, V., Kao, C. H.-J., Karunasinghe, N., Prasanna, K., Pallati, R., ... Narayanan, A. (2018). Aggressive and Non-Aggressive Prostate Cancer: Two Sides of the Same Coin or Two Different Coins?. Paper presented at ANZUP Annual Scientific Meeting, Putting People First, Sydney, NSW, Australia. 8 July - 10 July 2018. Asia-Pacific Journal of Clinical Oncology. (pp. 2). Related URL.
- Karunasinghe, N., Ambs, S., Wang, A., Tang, W., Zhu, S., Dorsey, T. H., ... Ferguson, L. R. (2018). Influence of lifestyle and genetic variants in the aldo-keto reductase 1C3 rs12529 polymorphism in high-risk prostate cancer detection variability assessed between US and New Zealand cohorts. PloS one, 13 (6)10.1371/journal.pone.0199122
- Piazzolla, V., Panunzio, M. F., Caporizzi, R., Cela, E. P., Di Martino, V., Antoniciello, A., ... Conversano, M. (2018). "Five-A-Day" and the Med-Food Anticancer Program. Annali di igiene : medicina preventiva e di comunita, 30 (1), 73-74. 10.7416/ai.2018.2199